During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

Studying mice, researchers have discovered that roseolovirus can trigger autoimmunity in a previously unknown way: by disrupting the process by which immune cells learn to avoid targeting their own ...

A single signaling pathway controls whether immune cells attack or befriend cells they encounter while patrolling our bodies, researchers at Stanford Medicine have found. Manipulating this pathway ...

Autoimmunity When our bodies are exposed to a virus — or any infection — it recognizes proteins and other molecules on the invading virus as “not us.” Scientists refer to this as an antigen. We then ...

The immune system defends the body against a wide range of internal and external threats. However, this versatility becomes an issue when immune mechanisms target host cells instead—a phenomenon ...

Summary of the research: This study revealed that T cells can discriminate between self- and neoself- antigens, and that neoself-reactive T cells are involved in causing autoimmune diseases. Osaka, ...

Please provide your email address to receive an email when new articles are posted on . van Trotsenburg and Mooij are pediatric endocrinologists at Emma Children’s Hospital, Amsterdam University ...

Please provide your email address to receive an email when new articles are posted on . Despite massive studies representing millions of participants that demonstrate associations between COVID-19 and ...