Chronic and viral infections can literally exhaust certain key cells in the immune system from a constant barrage of attacks.

Clonally expanded CD8+ T cells are key drivers of alopecia areata, mediating epithelial cell death and immune infiltration. JAK inhibitors are approved for AA treatment, but recurrence is common, ...

In a recent study published in Nature Methods, researchers developed "scAtlasVAE," a deep-learning model to integrate large-scale single-cell ribonucleic acid (RNA) sequencing (scRNA-seq) data, ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells. CD8 + T ...

CD8+ T cells accumulate in atherosclerotic plaques. Researchers identify a crucial signaling pathway -- with therapeutic potential. CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers ...

Killer immune cells destroy cancer cells and cells infected by virus. These CD8 + T cells are activated after detection of viral infection or growth of "non-self" tumor cells. However, in chronic ...

Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

Much like how a shot of espresso might re-energize you to get through the day, cancer immunotherapies have been developed to re-energize anti-tumor immune responses to help clear cancerous cells. When ...