Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

A team at Roswell Park Comprehensive Cancer Center has identified a novel metabolic pathway that plays a key role in enabling ...

Unlike accidental cell death, some cells can actively decide to die through a controlled process. This is called programmed ...

Image Caption: Controversial effects of the STING pathway in colitis development. In colon cancer, the pathway shows a similarly complex profile. Activation of STING can stimulate immune defenses that ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Scientists have uncovered a hidden weakness in one of the deadliest childhood cancers. The tumors, which spread quickly and are notoriously hard to treat, rely on a sugar-processing pathway to survive ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% ...