Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is ...
Oncology encompasses the study, diagnosis and treatment of neoplastic diseases, while carcinogenesis describes the multistep process by which normal cells acquire genetic and epigenetic alterations ...
Colorectal carcinogenesis arises from a multistep accumulation of genetic and epigenetic alterations that transform normal colonic epithelium into malignant lesions. Key driver events include ...
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