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Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging
Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons ...
Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...
Microglia, the immune cells that protect the brain, are thought to maintain a healthy brain environment by removing unwanted substances through dynamic remodeling of the actin cytoskeleton, the cell's ...
Scientists have attempted to map the human cell since the first microscope was invented more than 400 years ago. But many components of the cell still remain uncharted. "We know each of the proteins ...
A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
That means researchers can now use it to better understand how genes function, how diseases start and how to design better treatments. "Every single cell can have a different chromosome structure," ...
Meghna Gupta, Ph.D., is driven to improve fundamental scientific understanding of peroxisomes Meghna Gupta, Ph.D., a ...
Christophe Leterrier uses advanced microscopy to uncover neurons’ intricate nanostructure and dynamics while creating ...
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