Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...