The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Disseminated intravascular coagulation (DIC) is a severe systemic disorder characterised by paradoxical clotting and bleeding, commonly triggered by sepsis – the body’s dysregulated response to ...

Coagulation disorders refer to conditions that affect how the body controls blood clotting. This can mean the body forms too many or too few blood clots. Coagulation disorders are usually due to a ...

Blood clotting can lead to life-threatening heart attacks and strokes, and current treatments can lead to excessive bleeding and other worrisome side effects. But researchers now say they've found a ...

Researchers at Kumamoto University have developed a highly sensitive blood test that can detect subtle differences in how easily blood begins to clot, offering new possibilities for tailoring ...

Disseminated intravascular coagulation (DIC) is a condition that affects your blood’s clotting abilities. It can either set in slowly or happen very suddenly under particular conditions. It’s also ...

Researchers at Oregon Health & Science University have uncovered how a molecule found on certain bacteria may drive blood clotting in sepsis, a life-threatening condition that causes about 8 million ...

A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

Using a high-sensitivity blood test (SMAT) that measures initial thrombin generation (ITG)—the very first step of blood clot formation—the researchers analyzed blood samples from 771 patients with ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...