In cells, DNA is transcribed into RNAs that provide the molecular recipe for cells to make proteins. Most of the genome is transcribed into RNA, but only a small proportion of RNAs are actually from ...

Genes code for proteins, which are the cornerstone of many biological processes. The genome holds the instructions for making them in protein-coding genes and controls their activity with regulatory ...

If some function is not found for conserved non-coding regions even after an exhaustive array of functional assays, evolutionary models may need to be revised 78,80. Annotating lincRNAs.

When it comes to identifying cancer-driving mutations, research has focused almost exclusively on understanding how mutations in the coding region of genes may alter a protein’s function to promote ...

Many sections of the non-coding region of the human genome play a key role in regulating gene activity. But the relationship between non-coding mutations and cancer risk has been a mystery. New ...

Non-coding DNA changes the genitals you're born with Date: June 14, 2018 Source: The Francis Crick Institute Summary: Male mice grow ovaries instead of testes if they are missing a small region of ...

Berger and Daniel Bose, PhD, a postdoctoral fellow in her lab, study the regulation of gene expression from enhancers, non–coding regions of the genome more distant from protein-coding regions.