Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study ...

The polysaccharide β-1,2-glucan consists of repeating units of glucose linked together by β-1,2-glycosidic bonds. Cyclic β-1,2-glucans (CβGs) occur in different bacterial species and have a role in ...

Iridoid-producing plants use a cyclase to synthesize the characteristic double-ring structure of this important class of defense compounds and medically relevant substances Iridoids are a widespread ...

A reaction scheme showing an aryl aldehyde and a primary amine coming together on the left, with an arrow labeled with catalysts and ultraviolet light, to form a six-membered nitrogen-containing ring, ...

Macrocyclic compounds are ring-shaped molecules made by connecting two ends of linear molecules. One of their unique and exciting properties is that their cyclical configuration reduces their ...