A new review was published in Volume 13 of Oncoscience on May 22, 2026, titled "Adaptor proteins regulating tumor-associated macrophage polarization during cancer progression." ...
The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...
Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites seeding new resistant tumors elsewhere in the body. Combating the problem has ...
Researchers have uncovered a previously unrecognized pathway linking lung tumor genetics, diet, and the nervous system that drives cancer-associated cachexia, according to a new study in mice.
In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become ...
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...
Autophagy is the process by which cells remove damaged proteins, recycle worn-out organelles (e.g., mitochondria), clear ...
Microscopic images of cranial blood vessels show the growth of mulberry-shaped CCMs over a 21 day period in control mice (top two rows). This growth is prevented by treatment with the TIE2 inhibitor ...