Researchers have identified two ion channel switches that regulate the release of dopamine in the brain, a first step that might one day lead to therapeutics for a wide range of diseases and disorders ...

For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of pleasure, motivation, and reinforcement. In popular understanding, higher ...

Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that ...

My colleagues and I recently found that we were able to train mice to voluntarily increase the size and frequency of seemingly random dopamine impulses in their brains. Conventional wisdom in ...

Mice are both aware of random dopamine signaling in their brains and can willfully control it, according to new research from UC San Diego. The study was published in Current Biology. In previous ...

Dopamine: It's not just for rewards anymore. In a new Northwestern University-led study, researchers identified and recorded from three genetic subtypes of dopamine neurons in the midbrain region of a ...

A research team from the University of California, Irvine is the first to reveal that a molecule in the brain – ophthalmic acid – unexpectedly acts like a neurotransmitter similar to dopamine in ...

Synthetic biology has significantly advanced the design of synthetic trigger-controlled devices that can reprogram mammalian cells to interface with complex metabolic activities. In the brain, the ...

Dopamine agonists are a form of drug that treats conditions such as Parkinson’s disease. Dopamine agonists imitate dopamine, which is a chemical that is important for various physical and mental ...