Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

A Purdue University team published a comprehensive review highlighting two decades of research advancing desorption electrospray ionization-mass spectrometry (DESI-MS) as a rapid, sensitive, and ...

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Reading and writing DNA were once the rate-limiting step in synthetic biology workflows. This has been replaced by the search for the optimal target sequences to produce systems with desired ...

Although present in very small amounts, selenium (Se)-based compounds play important roles in protecting the body from ...

A tool developed by IU professors is on the market and foreseeing developments in gene therapy, environmental science and ...

Ambient ionization complements chromatographic workflows, offering rapid chemical composition snapshots and aiding in sample analysis. Chip Cody discusses his work in mass spectrometry, including DART ...

Biotherapeutics such as monoclonal antibodies, fusion proteins, peptides and cytokines are increasingly complex, creating challenges for rapid and accurate quality characterization. Traditional liquid ...

A detailed examination of top-down proteomics and its critical role in comprehensive proteoform identification using advanced ...

Selenium-based compounds play vital roles in human and animal health; however, accurately detecting their various forms has long been a challenge. Researchers from Chiba University have developed a ...