The reproducibility crisis in biomedical research presents a new challenge for conducting harm-benefit analysis: how do we improve the validity of studies to maximize the likelihood of benefit? Every ...

The term 'compliance' describes behaviors or actions that are in accordance with regulations or standards 1. In research using animals, written standard operating procedures and good laboratory ...

Non-surgical transfer techniques for mouse embryos and sperm provide animal welfare benefits for assisted reproduction of mice. While surgical embryo transfer (ET) is an effective method for transfer ...

Scientists at the University of Bristol's second Animal Welfare and Research 3Rs symposium, held earlier this year, had the opportunity to find out about current research and share best practice of ...

The concept of the 3Rs remains more prevalent than ever in global discussions related to humane animal use in aspects of research, teaching and testing. The 3Rs serve as a touchstone, in terms of ...