Definition: The extracellular matrix is the non-cellular network of proteins and polysaccharides that surrounds cells, gives tissues mechanical structure, and provides biochemical and mechanical ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...

Extracellular vesicles are defined as nanosized to microsized particles, delimited by a lipid bilayer membrane, that seem to be released by all cell types and that can transport bioactive molecules ...

The full 1 H-13 C HSQC spectrum indicated that neither proteins nor polysaccharides were present in the NA gel isolate (Supplementary Fig. 1) 21. eDNA fibre networked structures were visible in the ...

Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...

The tissue in our body can only hold together if the cells adhere not only to each other, but also to extracellular structures, such as collagen fibers of the connective tissue and the skin. How ...

In normal mice, neurons in the deep cerebellar nuclei are surrounded by PNNs and show robust neuronal activity during social interaction, allowing normal transmission of signals through ...

In a recent study published in Scientific Reports, a group of researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein (MOMP) protein of Chlamydia ...

Researchers at Kanazawa University have identified a previously unrecognized mechanism by which structural changes in the ...

Fascia of live mouse pancreas, in which the extracellular matrix is labeled with Rhobo6 (red) and nuclei are labeled with Hoechst (cyan). Maximum intensity projection shown. Before arriving at Janelia ...