A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably ...

Two papers in PNAS add to the growing body of work aimed at understanding the molecular interactions involved in the formation of amyloid fibrils (see related news story). Writing in last week's early ...

The Aβ fibrils that form amyloid plaques come in many shapes and sizes. According to a study published in Nature on January 4, unique assortments of Aβ fibril structures may underlie different ...

Credit: COURTESY OF MICHAEL SAWAYA, DAVID EISENBERG/UCLA" /> Credit: COURTESY OF MICHAEL SAWAYA, DAVID EISENBERG/UCLA The paper: R. Nelson et al., "Structure of the cross-β spine of amyloid-like ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 15 (April 12, 2022), pp. 1-10 (10 pages) In neurodegenerative diseases including Alzheimer’s and ...

The amyloid fibril in senile systemic amyloidosis (SSA), like that of familial amyloidotic polyneuropathy, is derived from transthyretin (TTR). SSA, however, is a common disease, affecting to some ...

Many scientists believe that plaques made of amyloid peptide contribute to brain degeneration in people with Alzheimer’s disease. Moreover, fibrils of a 42-amino-acid fragment of this peptide are ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primarily respiratory virus. It is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. In severe or ...

StarStuff image of the week This image isn't a close-up from the garden, but an active area of strong magnetic fields on the Sun's visible surface, the chromosphere. The petal-like structures ...