Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T ...
The virus-mimetic fusogenic nanovesicle (FuNV) can efficiently fuse with T cell in vivo, thereby delivering the loaded anti-CD19 (αCD19) chimeric antigen receptor (CAR) onto T cells to produce αCD19 ...