Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in ...

A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...

Siglec-15 has traditionally been understood as an immune checkpoint molecule, primarily located on the cell membrane where it suppresses T-cell function. However, the new research revealed that in SHH ...

Please provide your email address to receive an email when new articles are posted on . Adverse events reported with ENV-101 have been seen with other hedgehog inhibitors. Another trial is already ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...