PROVIDENCE, R.I. [Brown University] — Tiny, transient loops of genetic material, detected and studied by the hundreds for the first time at Brown University, are providing new insights into how the ...

We present the first large-scale identification of lariats—the transient branched introns that are released as a byproduct of pre-mRNA splicing. The locations of the branchpoints in these introns ...

Although the participation of spliceosomes is almost always required for intron removal, a few types of genes have self-splicing RNA introns. The RNA transcript of such a gene can carry out the entire ...

Lariats are discarded byproducts of RNA splicing, the process by which genetic instructions for making proteins are assembled. A new study has found hundreds more lariats than ever before, yielding ...