Thirty years after its discovery, scientists are eyeing leptin with renewed interest, for everything from weight loss drug ...

Leptin is a cell-signalling hormone vital in the regulation of appetite, food intake and body weight. Studies have shown that an absence of leptin in the body or leptin resistance can lead to ...

Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults in Korea. Lower baseline leptin was associated with a greater increase in tau over 2 ...

Twenty years after the hormone leptin was found to regulate metabolism, appetite, and weight through brain cells called neurons, Yale School of Medicine researchers have found that the hormone also ...

Leptin plays an important role in regulating appetite and body weight. Leptin binds to a form of leptin receptor present in the cells of the hypothalamus. This stimulates an intracellular signalling ...

Figure 1: Body weight gain, food intake and plasma insulin and leptin levels in chow-fed mutant mice and wild-type littermates. Figure 4: a and b, Measures of glucose homeostasis in mutant mice (M) ...

New research offers insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. The findings advance knowledge about leptin and weight gain, and also suggest a potential ...

The adipocyte hormone leptin is important in regulating energy homeostasis. Since severe lipodystrophy is associated with leptin deficiency, insulin resistance, hypertriglyceridemia, and hepatic ...