Tumors were eradicated in 30% of mice receiving cGAS LNPs injected into the tumor, in combination with immune checkpoint blockade.
In a recent study published in the journal Nature Reviews Drug Discovery, researchers collate available literature on medical and industrial developments aimed at reducing the cellular toxicity of ...
ATLANTA—An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by ...
The findings reveal that LNPs come in a surprising variety of configurations and the differences correlate with their ...
Johns Hopkins researchers have identified minuscule particles that supercharge therapeutic cancer vaccines, which train the immune system to attack tumors. These new lipid nanoparticles—tiny ...
Lipid-based nanoparticles are a popular research area as a non-viral platform for delivering RNA molecules and include liposomes, lipoplexes, lipid nanoparticles and solid lipid nanoparticles. Using ...
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New approach harnesses tumor's own machinery to produce immune-stimulating molecules
By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, MIT researchers ...
Lipid nanoparticles (LNPs) are the delivery vehicles of modern medicine, carrying cancer drugs, gene therapies and vaccines ...
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