Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Multivalent interactions between biological molecules result in the formation of biomolecular condensates, a phenomenon known as Liquid–liquid phase separation (LLPS). Biomolecular condensates have ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

The prion protein forms functional condensates that are enriched at cell-cell interfaces. However, long exposure to copper ions/hydrogen peroxide that result in oxidative stress, triggers a ...

Princeton bioengineer Clifford Brangwynne has been named a 2025 Keio Medical Science Prize Laureate for his discovery of liquid-liquid phase separation in cells. Japan’s Keio University awards the ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential ...

Membraneless organelles in cells contain high concentrations of semi-extractable RNAs, which could serve as potential biomarkers and drug targets. However, the identification and characterization of ...

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the ...

A research team from Andhra University has identified a molecular process that may help the Coronavirus escape the antibodies ...