Endochondral ossification requires proper control of chondrocyte proliferation, differentiation, survival, and organization. Here we show that knockout of α-parvin, an integrin-associated focal ...

Bone has long been acknowledged as a fundamental structural entity that provides support and protection to the body’s organs. However, emerging research indicates that bone plays a crucial role in the ...

Around 500 million years ago, early vertebrates in the seas became fish, adopting an inner skeleton and a flexible spine based on a nanocmposite of fibers and mineral, known as bone material. This ...

The From Labs to Lives Blog connects everyday topics with UC Davis research. Each post is reviewed by our experts, ensuring you always get useful information you can trust. Because we can’t see them, ...

What keeps bones able to remodel themselves and stay healthy? A team has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load. The ...