Loop diuretics are widely used in the management of edema and heart failure. They are also widely misunderstood. The reason is this: Loop diuretics are often prescribed in a dose-dependent strategy.

Diuretics are a class of medications commonly known as "water pills." There are several different classes of diuretics, each of which works differently in the kidneys to help rid the body of extra ...

Over time, the retention of sodium leads to crackles, peripheral edema, hepatomegaly with ascites, increased blood volume, and increased cardiac filling pressures. Although diuretics do not directly ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Please provide your email address to receive an email when new articles are posted on . Acute and chronic HF are associated with sodium retention leading to volume overload and edema. Much of the ...

The investigators of a new study have shown that the use of loop diuretics might be an initiating factor in the early pathogenesis of secondary hyperparathyroidism. “Loop diuretics are known to ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...