Nature Medicine has partnered with the American Statistical Association (ASA) to facilitate the timely, consistent, and thorough statistical peer review of clinical trials. The statistical ...

In this issue, Tadesse and colleagues investigated transmission after a dry-season malaria outbreak in Dire Dawa, Ethiopia. Spatial clustering of Plasmodium ...

In this issue, Widschwendter and colleagues establish that screening of cervical cancer using a DNA methylation-based triage showed better performance than ...

The cover illustration showcases the concept and functionality of the machine-learning model developed by Liu et al. to identify and assist in the diagnosis ...

MicroRNAs (miRNAs) have emerged as crucial mediators of human disease, but their roles in autoimmunity have only recently been appreciated. A new study using mouse and human tissues from various ...

Developed through systematic review and expert consensus, the REP-EQUITY toolkit provides a seven-step guide for investigators to facilitate representative and equitable recruitment into clinical ...

Germline predisposition plays a major part in myelodysplastic syndromes in children. Sahoo et al. report that germline mutations in the genes SAMD9 and SAMD9L account for 8% of pediatric ...

Conventional mesenchymal stromal cell (MSC)-based manufacturing approaches are hampered by challenges with scalability and inter-donor variability, which ...

Premature infants often undergo repeated episodes of hypoxia and can develop a condition called encephalopathy of prematurity with long-term neurodevelopmental impairments. In this issue, Paşca ...

We asked experts around the world what surprised them about SARS-CoV-2 and COVID-19, and what questions remain unanswered. Nature Medicine asks leading researchers to name their most anticipated ...

Extreme heat events are expected to become more frequent because of climate change. Our analysis of almost 140,000 births across 16 hospitals in four countries in sub-Saharan Africa indicates 34% ...

Analyses of the year 2023, the warmest on record globally, estimated 47,690 heat-related deaths across 35 countries in Europe, which would have been 80% higher in the absence of any societal ...