In patients with gout starting allopurinol as a long-term urate-lowering therapy, the prophylactic use of nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with a higher risk for major ...

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

Mr. M’s height is 5’9″, weight is 195 lb, body mass index is 28.8 kg/m 2, and BP is 128/78 mm Hg. The left great toe is swollen, warm, erythematous, and tender to touch, with chronic synovial changes.

Once gout has been diagnosed, the cause of the hyperuricemia should be identified. The two most common causes of hyperuricemia are decreased renal elimination of urate and excessive alcohol intake. A ...

In the U.S., six non-steroidal anti-inflammatory drugs (NSAIDs) are most commonly used to manage pain and inflammation. While this drug class is widely relied upon, it is also associated with ...