Biological droplets are dynamic and transient assemblies of biomolecules that undergo phase separation within cells. Unlike traditional organelles bound by membranes, biological droplets form through ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

A new RNA type, smOOPs, has been found to drive biomolecular condensate formation in early development, offering new insight ...

Six feet of DNA crammed into a cell nucleus narrower than a human hair: ...

Chemical engineering professor Dr. Jeetain Mittal has received a National Institutes of Health grant to support his work on phase separation. Mittal’s research focuses on developing a multiscale ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

This video shows how the length of linker DNA connecting the nucleosomes affects how the structures are arranged, which in turn affects the interactions between chromatin fibers and the network ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...

This is a preview. Log in through your library . Abstract The role of biomolecular condensates in regulating biological function and the importance of dynamic interactions involving intrinsically ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 36 (September 6, 2022), pp. 1-7 (7 pages) Understanding the physical principle that governs the ...