Cells organize their molecules into distinct functional areas. While textbooks usually refer to membrane-bound organelles ...

Targeted protein degradation (TPD) approaches including PROTAC and molecular glue have revolutionized drug discovery. However, in part due to complication of the ubiquitination and related ...

These include stress granules and proteasome storage granules (PSGs). In the past, these membraneless organelles were only visible as “droplets” using a fluorescence microscope. Now, researchers from ...

Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants. In one current study, they have focused on the disease ...

Scientists have uncovered a previously unknown function of the immune system that could pave the way for new antibiotics. The discovery, made by researchers in Israel, revealed that a part of the body ...