The most common method used to study protein structures is X-ray crystallography ... of the thousands of atoms within the protein crystal. How Do Proteins Arrive at Their Final Shapes?

Now, Tokyo Tech researchers have addressed this issue with a novel pipeline that enables a rapid crystal structure analysis of IDPs via a cell-free protein crystallization technique. Many people ...

his algorithms can even advise researchers which bits of a protein to truncate to boost chances of getting a crystal structure. He is making plans to undertake a similar project for membrane ...

To determine the three-dimensional structure of small proteins such as transthyretin, researchers often turn to crystallography, in which proteins are forced into a large, repetitive crystal ...

Breathing, eating, sleeping, running to Taco Bell in the middle of the night – none of these activities would be possible ...

Sundaralingam. After her thesis research on crystal structures of protein synthesis inhibitors, Smith pursued a growing interest in protein structure by joining Wayne Hendrickson at the Naval Research ...

Unlike their well-known, folded counterparts, intrinsically disordered proteins lack a single, stable three-dimensional structure. Instead, like Proteus, they take on many different conformations. 1 ...

When the team analyzed the transthyretin on the grid, they found that the protein forms asymmetric structures with two differently shaped binding pockets. Based on the more than 200 crystal ...