Researchers have figured out a way to make an RNA biosensor that fluoresces when it encounters small inorganic metabolites—not by engineering the RNA but by adjusting its fluorogenic ligand molecule.
RNA aptamers are short, single-stranded oligonucleotides that adopt unique three-dimensional structures, enabling them to bind selectively to fluorogenic dyes and other small molecules. Engineered to ...
PARIS--(BUSINESS WIRE)--A new research study published in Nature Communications highlights how Depixus’ scalable single molecule technology can provide detailed mechanistic insights into RNA-ligand ...
Golden Broccoli: Utah biochemists create first single-dyed ratiometric biosensor for glycine imaging
The pop art-inspired illustration highlights a new light-up RNA aptamer called Golden Broccoli that was developed through structure-based design. The amino acid glycine is an important ...
We have all heard of antibodies – proteins produced by our bodies to bind to viruses or bacteria, marking them for elimination by the immune system. But not all of us are familiar with aptamers: short ...
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