RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

DeepChopper model improves RNA sequencing research by mitigating chimera artifacts

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...
News Medical

Deep learning revolutionizes RNA 3D structure prediction with RhoFold+

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...
Science Daily

Testing thousands of RNA enzymes helps find first 'twister ribozyme' in mammals

A new method can test the activity of thousands of RNA enzymes, called ribozymes, in a single experiment. The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA ...
The Brown Daily Herald

Meet the Brown researcher who wants to help sequence all potential RNA modifications

In 2020, Juan Alfonzo, a professor of molecular biology, cell biology and biochemistry, began a project out of “pure COVID boredom.” Now, that project may become the largest scientific undertaking ...