Controlled study designed to confirm previous compelling efficacy with preliminary data expected by the end of 2026 Pelareorep-based treatment regimen recently granted Fast Track Designation in 2L ...

Low dose alnodesertib plus gemcitabine met the primary endpoint of progression-free survival (PFS) versus gemcitabine alone ...

A 20-year follow-up of older adults in the ACTIVE randomized trial linked to Medicare claims found that speed of processing cognitive training with booster sessions was associated with a significantly ...

An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox ...

Intellia said the FDA removed the clinical hold on application for the Phase 3 clinical trial of nexiguran ziclumeran. The study is a randomized, double-blind, placebo-controlled trial evaluating the ...

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, ...

The results of a randomized controlled trial (RCT) indicate that meningococcal B vaccine is not effective at preventing ...

Effect on Travel Distance of a Statewide Regionalization Policy for Initial Breast Cancer Surgery The use of 90 mg/m 2 daunorubicin once daily in the context of classical 7 + 3 induction does not ...

Phase 1b/2 study of arfolitixorin in combination with 5-fluorouracil (5FU), oxaliplatin, and bevacizumab as first-line therapy for metastatic colorectal cancer (mCRC). CR, complete response; DOR, ...

Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not been established. We randomly assigned participants 45 to 85 years of age ...