What is Single-Molecule Localization Microscopy? Single-molecule localization microscopy (SMLM) is a super-resolution imaging technique that enables the visualization of biological structures and ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

In a recent study published in Nature Communications, researchers developed a €350 smartphone-based microscope that can detect individual molecules. This brings super-resolution, research-grade ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and ...

In a study published in Science Advances, a team of bioengineering researchers at the University of Illinois Urbana-Champaign developed an algorithm known as adaptive intersection maximization, or AIM ...

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic ...

Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconvolution.

By combining two fundamentally different microscopy techniques, researchers can now measure the optical properties of a ...