Extreme normality in superficial or seemingly inconsequential matters can be a sign that something is deeply wrong. This thought may have occurred to scientists at the University of Colorado (CU) ...
Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men. While early-stage disease can be effectively managed, advanced forms-particularly metastatic ...
Image Caption: The role of SOX2 in lineage conversion from CRPC to NEPC. SOX2’s role in treatment resistance is particularly significant. It supports resistance to chemotherapy by inducing a ...
Sox2 is a stem cell protein that’s known to proliferate after a spinal cord injury. Now researchers at UT Southwestern and Indiana University are proposing a method for harnessing the protein to ...
Squamous cell carcinomas (SCCs) are aggressive malignancies arising from squamous epithelium of various organs, such as esophagus, head and neck, lung and skin. Previous studies demonstrated that two ...
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DNA nanomachine strategy reverses chemoresistance in small cell lung cancer
Professor Chao Zhang's team at Zhujiang Hospital, Southern Medical University, has developed a novel DNA nanomachine-based drug delivery and release strategy aimed at overcoming chemoresistance in ...
Randomized phase III trial of pixantrone compared with other chemotherapeutic agents for third-line single-agent treatment of relapsed aggressive non-Hodgkin's lymphoma No significant financial ...
Researchers at UT Southwestern (UTSW) and Indiana University have used genetic engineering techniques to trigger the production of functional nerve cells from scar-forming cells in mouse spinal cords, ...
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