Spatial transcriptomics cancer research is reshaping how tumors are understood. What a malignant cell does depends not just on its genome but on where it sits: adjacent immune populations, stromal ...

Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies ...

Explore next-generation oncology biomarker discovery using RNA-seq, liquid biopsy, and spatial transcriptomics to advance ...

Newswise — Prostate cancer (PCa) is a highly prevalent malignancy, heavily characterized by complex cellular heterogeneity and highly variable clinical outcomes. The Gleason score (GS) remains the ...

Entering inside a tumor to reconstruct its geography and deeply understand the mechanisms of interaction between different ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

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Comparison of dose-dense versus standard neoadjuvant chemotherapy for HER2 negative breast cancer: Retrospective, multicenter, real-world, Japanese study (JONIE5). MRI concentric partial response ...