Researchers identified organised T-cell and dendritic-cell niches that may contribute to persistent inflammation in atopic ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) are often framed as rivals, but they answer different questions about the same tissue. Single-cell RNA-seq resolves cell identity at ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Spatial transcriptomics quality control (QC) determines whether a costly assay produces trustworthy biology or an expensive pile of noise. Because both sequencing- and imaging-based platforms are ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...