The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...

Patterns of alternative splicing of mRNA differ between tumors and the normal tissues from which they are derived. 2 It has been recognized for some time that aberrant splicing may produce neoantigens ...

Alternative splicing has a key role in generating protein diversity, affects the expression of nearly 70% of human genes and is implicated in a wide variety of human diseases. The regulation of ...