Doctors discovered a woman had "blood chimerism" after examining the chromosomes of cells from different parts of her body.

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about ...

Chromosomal translocations occur in leukemias, lymphomas, sarcomas and some epithelial tumors and some generate unique fusion proteins. These translocation products may provide tumor-specific targets ...

The mitotic checkpoint is a major cell cycle control mechanism that acts to guard against chromosome missegregation and the subsequent production of aneuploid daughter cells. Aneuploidy is a ...

The data, which is being presented at this year's AMP meeting, offers some insights into the often hidden causes of recurrent pregnancy loss.

Chromosomal abnormalities are a random occurrence, but very common in women over 35 years. Chromosomal abnormalities occur due to various reasons out of which only 5% are genetic. An abnormal sperm, ...

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell ...

A new tool, ContactTracing, enabled researchers to show that chronic activation of the STING pathway, induced by chromosomal instability (CIN), promotes downstream changes in cellular signaling. This ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Researchers have revealed the mechanisms by which cells enter senescence because of an imbalance in the number of chromosomes. Chromosomal instability is a common trait in most solid tumors, such as ...