The Cryo-Electron Microscopy Center supports industry, academic, government, and non-profit research institutes, providing single-particle and microcrystal electron diffraction capabilities. We offer ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

A custom-designed electron cryomicroscope operating at 100 keV promises to minimize the expense and complexity of biological structure research. Although electron cryo-microscopy (cryo-EM) has shown ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Researcher Ankita Dhar and facility manager M. Jason de la Cruz at work in MSK's cryo-electron microscopy facility, where MSK's new fourth-generation Krios microscope (far left, behind the glass) ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

In conjunction with the Structural Biology Core Facility, CEMIL enables practitioners of Cryo-EM within MSK laboratories to design innovative experiments and collect the highest quality Cryo-EM data ...

Multicolored 3D rendering of a muscle fiber. It looks a bit like a bundle of yarn, with lots of short, aligned strands. A 3D rendering of the proteins in a muscle fiber, captured by cryo-electron ...

Electron microscopy has become a vital tool in structural biology, enabling researchers to visualize biological macromolecules at near-atomic resolution. Recent advances have transformed it from a low ...

In this article, we look at some of the key developments of various microscopy techniques over the last few years and how they have benefitted different areas of research and development. The impact ...