How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

A study using Ribo-STAMP technology reveals that protein production in brain cells varies significantly between different types of neurons, offering new insights into autism and memory.

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time. But directly measuring this protein production, ...

In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...

Neurodegenerative diseases are commonly adult-onset conditions characterized by degeneration of specific neuronal populations. Familial forms are caused by mutations in single genes, but most patients ...

The brain's ability to carry out everything from forming memories to coordinating movement depends on its cells producing the right proteins at the right time. But directly measuring this protein ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time.

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Researchers from the Broad Institute and Massachusetts Institute of Technology (MIT) have engineered multi-tailed mRNAs that boost mRNA activity levels in cells by as much as 20x and last 2-3 times ...