AMHERST, Mass. - At present, medical researchers lack experimental models and urgently need new ways to study liver function and mechanisms, especially because liver disease is on the rise due to the ...
3D bio-printed liver model and high-content imaging for evaluating the toxicity effects of compounds
The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...
Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by ...
A new mouse study shows high-dose aluminum adjuvant Imject Alum can induce liver fibrosis via inflammasome activation, ...
ToxPredictor accurately predicts drug induced liver injury (DILI) to offer a valuable “go/no-go” tool in clinical decision making.
A team at Baylor College of Medicine and other institutions has developed a novel mouse model that reproduces many key features of human non-alcoholic fatty liver disease (NAFLD), a little-understood ...
Absorption, Distribution, Metabolism, and Excretion (ADME) are important parameters to determine the pharmacokinetic profile of a drug, and therefore a crucial measurement for drug efficacy. Animal ...
October represents a month of liver awareness, marked by many countries as a time to reflect on an incredibly resilient, yet vulnerable, organ. Liver disease is a growing problem worldwide, but ...
At the Liver Meeting sponsored by the American Association for the Study of Liver Diseases, investigators presented new ...
Researchers at Osaka Metropolitan University have developed an AI model that can detect fatty liver disease from routine chest X-rays with over 80 % accuracy, offering a low-cost, widely accessible ...
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