Patients with hereditary ATTR-CM were younger, had better myocardial function, and had higher arterial stiffness compared with patients with wild-type ATTR-CM. The type of mutation in the ...

The authors argue that the long-held label of "uniformly lethal" may no longer be appropriate and can inadvertently bias clinical decision-making. Homozygous achondroplasia is traditionally ...

Despite the suboptimal imaging conditions, TTE and CMR measurements of LVEF demonstrated high agreement, with a mean difference of 1.6%. Transthoracic echocardiography (TTE) and cardiac magnetic ...

Patients with MG who took C5 inhibitors saw greater reductions in concomitant OCS and NSIST use than did those who took efgartigimod. Rare Disease Advisor, a trusted source of medical news and feature ...

Individuals with advanced liver disease may also experience significant weight loss due to nausea and poor appetite. Candidates for liver transplantation may need to gain weight to optimize surgical ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare acquired autoimmune neurological disorder in which both T-cell-mediated and humoral immune mechanisms target healthy myelinated ...

The recommendations were based on the available evidence, its certainty, and key judgments using the Grading of Recommendations Assessment, Development and Evaluation framework. New guidelines ...

In classical PNH, disease is present with the absence of bone marrow disease. 3 Patients with classical PNH typically have severe intravascular hemolysis along with an elevated reticulocyte count, a ...

Higher macrophage density in the tubulointerstitium was associated with progression to end-stage kidney disease. A new study has evaluated the density and prognostic significance of CD68+ macrophages ...

Immunohistochemistry analyses detected a correlation between increased CDK1 expression and higher levels of LDH, a key indicator of greater disease severity in DLBCL. Higher levels of CDK1 expression ...

Results showed a significantly higher prevalence of liver disease among patients with chronic pruritus compared to healthy controls. Patients with liver diseases of different etiologies, including ...

Immune repertoire diversity differed by hemophilia type, with hemophilia A showing more B cell clonotypes and hemophilia B demonstrating higher T cell diversity. Patients with severe hemophilia A and ...