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Cancer Research6d
Artificial Intelligence–Driven Cancer Diagnostics: Enhancing Radiology and Pathology through Reproducibility, Explainability, and Multimodality | Cancer Research | American ...
Abstract. The integration of artificial intelligence (AI) in cancer research has significantly advanced radiology, pathology, and multimodal approaches, offering unprecedented capabilities in image ...
Cancer Research1y
Abstract - American Association for Cancer Research
Abstract. Introduction: Antibody and peptide-conjugated drugs are rapidly entering the clinic for the treatment of patients with early and advanced breast cancer. These drugs are designed to achieve ...
Cancer Research7d
Ribociclib in Sequential Combination with Doxorubicin in Anthracycline-Naïve Advanced Soft-Tissue Sarcomas: Results of a Dose-Finding Phase Ib Study - American Association for ...
Doxorubicin-naïve patients with metastatic soft-tissue sarcoma were enrolled in this phase Ib study. Every 21 days, subjects received ribociclib daily for 7 days followed by 3 days of no treatment ...
Cancer Research5d
Response and Resistance to RAS Inhibition in Cancer Available to Purchase - American Association for Cancer Research
AbstractRAS inhibition has the potential to transform cancer treatment for many patients. The landscape of RAS inhibitor therapies is rapidly evolving, with two mutant-selective KRAS inhibitors now ...
Cancer Research6d
Paving a Path to Clinical Impact with Radiomics: Enabling Reproducibility and Reach Available to Purchase - American Association for Cancer Research
Abstract. Radiomics, the extraction of quantitative data from images, holds promise for noninvasively characterizing tumor phenotypes. Tools like LIFEx have improved the accessibility, transparency, ...
Cancer Research6d
Targeting Cancer-Associated Glycosylation for Adoptive T-cell Therapy of Solid Tumors Available to Purchase - American Association for Cancer Research
Chimeric antigen receptor (CAR) T-cell therapy has improved outcomes for patients with chemotherapy-resistant B-cell malignancies. However, CAR T-cell treatment of patients with solid cancers has been ...
Cancer Research7d
Antitumor Immunity Mediated by Engineered Stem Cells Exploiting TRAIL-Induced Cell Death and FLT3L Immunomodulation Available to Purchase - American Association for Cancer Research
AbstractPurpose:. Death receptor (DR)–targeted therapies offer a promising tumor cell–specific therapeutic strategy for highly malignant brain tumors, such as glioblastoma (GBM). However, whether ...
Cancer Research1y
Abstract - American Association for Cancer Research
Abstract. The Hippo pathway, a critical cell proliferation regulator, remains an underexplored oncogenic pathway in precision oncology. It is executed through YAP1/TAZ co-activators and the TEAD ...
Cancer Research2mon
Abstract - American Association for Cancer Research
AbstractBackground:. The five-year survival rate for colorectal cancer (CRC) remains at 14% despite improvements in early detection and the development of novel treatments, underscoring the need for ...
Cancer Research1y
Abstract - American Association for Cancer Research
Abstract. Background: Activating mutations in KRAS (including KRAS G12V) are well-described oncogenic drivers in solid tumors. Patients with KRAS driver mutations have a poor prognosis, and most ...
Cancer Research8d
Weizmann Institute Cancer Labs Destroyed, Damaged by Iranian Missile Available to Purchase - American Association for Cancer Research
An Iranian missile hit the campus of Israel’s Weizmann Institute of Science, destroying many cancer research labs. Researchers mourned the loss of expensive equipment and irreplaceable samples and ...
Cancer Research3y
Abstract - American Association for Cancer Research
Abstract. Background: The 3rd-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), like osimertinib, provide marked clinical benefit for EGFR-mutant non-small cell lung ...