Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

ConspectusChirality is ubiquitous in the universe and in living creatures over detectable length scales from the subatomic to the galactic, as exemplified in the two extremes by subatomic particles ...

l-Serine, a nonessential amino acid in humans, possesses significant physiological functions and is widely used in the food, cosmetic, and pharmaceutical industries. Driven by steadily growing market ...

A facile asymmetric synthesis of α,α-disubstituted amino acid derivatives was achieved via gold redox catalysis. The in situ formed aryl gold(III) served as the key intermediate toward alkyne ...

Au nanoclusters (NCs), with discrete electronic structures and tunable properties, are promising building blocks for nanoelectronics. However, maximizing their potential requires a deeper ...

Correction to “Stealth Polydopamine-Based Nanoparticles with Red Blood Cell Membrane for the Chemo-Photothermal Therapy of Cancer” ...

The potential toxicities of chemicals to humans and wildlife remain largely unknown. In vitro bioassays have increasingly been applied for the toxicity testing of chemicals. However, most of these ...

Herein, we investigated to which extent metallic nanoparticles (MNPs) affect the trophic transfer of other coexisting MNPs from lettuce to terrestrial snails and the associated tissue-specific ...

We herein disclose a mild and efficient cadmium-catalyzed domino reaction for accessing 1,6-enynes via a sequential A 3 -coupling/1,5-hydride transfer/hydrolysis/A 3 -coupling. This method ...

Protein–ligand binding affinity may be affected by protein mutations, especially point mutations occurring within the binding site, which may indirectly contribute to interindividual differences in ...

Low loose bulk density, a characteristic commonly observed in large accumulations of needle-like crystals, has caused numerous issues in both production processes and daily life. Antisolvent ...

Substituted cyclic alcohol is one of the pharmaceutically essential scaffolds. Here, we report photoredox/cobalt-catalyzed reductive cyclization of alkynals using H2O for the catalyst turnover. This ...