San Francisco 49ers running back Isaac Guerendo revealed how he learns from All-Pro teammate Christian McCaffrey.

The 49ers have committed to Brock Purdy with a big extension. But the key to that deal is the guy standing behind him in the ...

The 2024 campaign was a lost season for the San Francisco 49ers. Coming off a narrow, heartbreaking loss in Super Bowl LVIII, ...

NBC Sports NFL commentator Michael Holley has major concern for San Francisco 49ers over Christian McCaffrey entering 2025 ...

San Francisco 49ers star Christian McCaffrey's health will be a major factor in whether the 49ers return to form this season.

Going round by round through the first eight frames, here’s a look at some of the draft picks most likely to either ...

Facing WR challenges, the 49ers will lean on George Kittle and Christian McCaffrey, benefiting from a softer schedule. Brad ...

Christian McCaffrey has looked as good as ever at training camp, and Mike Florio and Michael Holley evaluate what to expect ...

San Francisco 49ers quarterback Brock Purdy confirms that Christian McCaffrey is fully prepared for the new season. This is the exact news that everyone wants to hear. After an extremely difficult ...

The 49ers may target Commanders RB Brian Robinson Jr. to add depth behind Christian McCaffrey and strengthen Shanahan’s offense.

Through just two preseason games, the 49ers already have four injured running backs -- Isaac Guerendo (shoulder), Patrick Taylor Jr. (shoulder), Jordan James (finger) and Corey Kiner (ankle). Their ...