Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.

Adipogenesis, the process of forming mature fat cells, is central to energy balance and obesity-related diseases. At the ...

Adults with Fabry disease were treated with isaralgagene civaparvovec (ST-920 or isa-vec), an alpha-galactosidase A gene therapy based on an adeno-associated virus. According to H.C. Wainwright ...

Objective Deep venous thrombosis (DVT), a potentially life-threatening condition with a high clinical incidence, represents a ...

Researchers are developing new strategies to drug the undruggable in cancer, including targeting intracellular KRAS with ...

A distinct natural killer (NK) cell subset, termed CLL_NK, is a precursor to effector NK phenotypes and serves as a critical immunologic marker in chronic lymphocytic leukemia (CLL), offering ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

Gene Earl Rouse, age 53, passed away on January 18, 2025, at the UW Hospital in Madison. He was born on May 6, 1971, in Kinston, North Carolina.

C. perfringens is a widespread bacterium found in the intestines of animals and humans, known for causing severe enteric diseases. It produces over 20 toxins, with the β-2 toxin (CPB2) being ...

They found i-motifs in the MYC gene family, whose activity is known to be dysregulated in around 70% of human cancers.