A Cambridge biotechnology company is eliminating nearly its entire workforce after federal regulators determined its only drug posed an unacceptable cancer risk. The move eliminates 48 positions and ...

Fulcrum Therapeutics will lay off the majority of its workforce after it said it would terminate the development of a sickle-cell-disease treatment. The company on Thursday said it expects to reduce ...

With few treatments available for sickle cell disease, encouraging early clinical data for a Fulcrum Therapeutics drug made it one to watch. But another medicine from the same drug class was recently ...

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Fulcrum Therapeutics (FULC) lost nearly 50% of its value in extended trading after the company disclosed plans to discontinue the development of its lead asset, pociredir, for sickle cell disease in ...

The oral drug, pociredir, was being tested to treat sickle-cell disease, an inherited blood disorder that can trigger pain, anemia and organ damage and reduce life expectancy. Sign up here. Pociredir ...

Fulcrum Therapeutics has scrapped its sole clinical-stage program after the FDA took a hard line on the modality following the recent withdrawal of Ipsen’s Tazverik from the U.S. market. Ipsen ...

June 1 (Reuters) - Fulcrum Therapeutics (FULC.O), opens new tab said on Monday it would stop developing its experimental sickle-cell disease drug after the U.S. Food and Drug Administration raised ...

Bob Baron, who founded and ran Fulcrum Publishing for more than four decades, died on April 24 in Denver, Colo. He was 92. Prior to beginning his career in publishing, Baron, who was born in Los ...

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To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min The team is in various stages of ...

A dispute between brothers at the helm of a prominent San Antonio real estate development company has erupted into a multimillion-dollar lawsuit, with allegations of deception, betrayal and actions ...