After years of false starts, metabolic dysfunction-associated steatohepatitis is finally seeing therapeutic breakthroughs — from the first approved drug to candidates that reverse cirrhosis.

Nature Medicine offers double-anonymized peer review; authors who choose this option will remain anonymous to the reviewers throughout the peer review process. If you want to participate in double ...

Nature Medicine has partnered with the American Statistical Association (ASA) to facilitate the timely, consistent, and thorough statistical peer review of clinical trials. The statistical ...

In this issue, Widschwendter and colleagues establish that screening of cervical cancer using a DNA methylation-based triage showed better performance than ...

In this issue, Tadesse and colleagues investigated transmission after a dry-season malaria outbreak in Dire Dawa, Ethiopia. Spatial clustering of Plasmodium ...

As Nature Medicine celebrates its 25th anniversary, we bring our readers a special Focus on Digital Medicine that highlights the new technologies ...

The use of transgenic pigs as a source of organs and tissues for patients in need could revolutionize medicine — but to achieve that goal, data from clinical trials and forthright assessment of ...

Germline predisposition plays a major part in myelodysplastic syndromes in children. Sahoo et al. report that germline mutations in the genes SAMD9 and SAMD9L account for 8% of pediatric ...

The cover illustration showcases the concept and functionality of the machine-learning model developed by Liu et al. to identify and assist in the diagnosis ...

Stockpiled A(H5N1) influenza vaccines made using viruses from the mid-2000s stimulate antibodies that cross-react with current strains, despite being separated by 20 years of viral evolution ...

This year brought wins for artificial intelligence, genomics and gene editing, and breakthroughs in understanding diseases whose underpinnings have long eluded scientists. Here is our selection of ...

Conventional mesenchymal stromal cell (MSC)-based manufacturing approaches are hampered by challenges with scalability and inter-donor variability, which ...