Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.
Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.
Researchers suggest that many metamorphic proteins have an 'underlying temperature dependence.' If confirmed, this would mean that temperature -- and cold temperature in particular -- plays a ...
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
A pair of University of Houston professors, known for their contributions to crystal engineering with specific breakthroughs ...
A-listers are hailing ‘wellness coffee’ as a miracle elixir, but what exactly are the benefits? Nutritionist Louise Pyne ...
Breathing, eating, sleeping, running to Taco Bell in the middle of the night – none of these activities would be possible ...
Scientists have made enormous advances in understanding the structures of proteins over the past several decades. Imaging technologies like cryo-electron microscopy and X-ray crystallography help ...
When the x-rays strike the crystal, they are scattered ... molecules where people have solved the structure, we could build a database of dynamics with which we can really make computational ...
This process involves the formation of amyloid fibrils, crystal-like collections of misfolded proteins that clump together when the proteins are highly concentrated (supersaturated) in liquids ...
Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia ...
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