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SOLVED:An alcohol will not react with aziridine unless the reaction is catalyzed by an acid. Why is a catalyst necessary? SOLUTION Although relief of ring strain is sufficient by itself to cause an epoxide to undergo a ring-opening reaction (Section 12.7 ), it is not sufficient to cause an aziridine to undergo a ring-opening reaction. A negatively charged nitrogen is a stronger base, and therefore a poorer leaving group, than a negatively charged oxygen. An acid, therefore, is needed to make the
SOLVED:An alcohol will not react with aziridine unless the reaction i…
May 13, 2020
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