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Rx Meds That Block Thyroid Conversion (Lowering T3) Some medications block your body from converting T4 into the active thyroid hormone T3. Without T3, you may feel tired, gain weight, or lose hair even if your TSH looks “normal.” What to know: • T3 is the most powerful thyroid hormone • Beta blockers, narcotics, antidepressants, and methimazole interfere with conversion • Low T3 = fatigue, weight gain, hair loss, brain fog If you struggle with symptoms despite “normal” labs, this could be the r
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